Microdosing

Archivio tematico

Il microdosing (l’assunzione regolare di dosi sub-percettive di sostanze psichedeliche) è una delle pratiche più discusse e meno comprese degli ultimi anni.
In questa sezione trovi articoli che analizzano i dati disponibili, i limiti metodologici degli studi, gli effetti riportati dalle persone che lo praticano e le domande ancora aperte su sicurezza, efficacia e aspettative.
Una panoramica utile per orientarsi in un fenomeno tanto popolare quanto controverso.

The difference between ‘placebo group’ and ‘placebo control’: a case study in psychedelic microdosing.
Szigeti, B., Nutt, D., Carhart-Harris, R. et al. The difference between ‘placebo group’ and ‘placebo control’: a case study in psychedelic microdosing. Sci Rep 13, 12107 (2023). https://doi.org/10.1038/s41598-023-34938-7

Trait mindfulness and personality characteristics in a microdosing ADHD sample: a naturalistic prospective survey study.
Haijen, Eline C H M et al. “Trait mindfulness and personality characteristics in a microdosing ADHD sample: a naturalistic prospective survey study.” Frontiers in psychiatry vol. 14 1233585. 16 Oct. 2023, doi:10.3389/fpsyt.2023.1233585

Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins.
Rouaud A, Calder AE, Hasler G. Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins. Journal of Psychopharmacology. 2024;38(3):217-224. doi:10.1177/02698811231225609

Neural complexity is increased after low doses of LSD, but not moderate to high doses of oral THC or methamphetamine.
Murray, C.H., Frohlich, J., Haggarty, C.J. et al. Neural complexity is increased after low doses of LSD, but not moderate to high doses of oral THC or methamphetamine. Neuropsychopharmacol. 49, 1120–1128 (2024). https://doi.org/10.1038/s41386-024-01809-2

Low nonpsychedelic doses of psilocybin for the therapy of MASLD.
EASL Congress 2024. Poster M. Colognesi et al.

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